Information related to research interest "AMPK, CaMKK2 kinase, metabolism, Type 2 diabetes"
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Supervisors with this research interest
Faculty of Health Sciences
Centre for Exercise and Nutrition
Bruce Kemp is an NHMC Fellow. He graduated (B. AgSc Hon University of Adelaide) with a PhD in Biochemistry (Flinders University) 1975. He undertook postdoctoral studies at UC Davis California in Edwin G Krebs (Nobel laureate) laboratory. His research interests are in the regulation of metabolism in response to metabolic stress and or exercise. He is a Fellow of the Royal Society, the Australian Academy of Science and the American Association for the Advancement of Science
: 0419488725 (Melbourne) : firstname.lastname@example.org
Mary MacKillop Institute for Health Research
I graduated from the University of Bath, UK (1998) and completed my Ph.D studies (2002) at King???s College London investigating iron acquisition in pathogenic Neisseria meningitidis. My first postdoctoral position uncovered molecular mechanisms and transporters responsible for dietary iron absorption in the duodenum. A move to Bruce Kemp???s lab at St. Vincent???s Institute, Melbourne in 2006 prompted a change in research fields to energy metabolism.
I formed the Metabolic Signalling Laboratory in 2014, a multi-disciplinary team employing biochemical, biophysical, structural and cell-based techniques to investigate signalling pathways controlling cellular metabolism. While maintaining a core interest in regulation of AMP-activated protein kinase (AMPK), the cellular fuel gauge and a drug target of great potential, we are now expanding our scope to incorporate other central metabolic kinases (e.g. ULK1, mTOR, CaMKK2) and associated pathways. I also lead efforts to develop small-molecule therapeutics targeting AMPK to treat metabolic diseases such as type 2 diabetes, cancer and neurodegeneration.
: (Melbourne, Level 5, 215 Spring Street) : Jon.Oakhill@acu.edu.au
Common Research Interests
No Common Research Interest is found