Dr Geraldine Mitchell - University and OBI Centre : AORTEC (Faculty of Health Sciences)

Assistant Supervisor – Only eligible to supervise with a fully accredited Principal or Co-supervisor

Geraldine Mitchell completed her PhD (University of Melbourne) on 'Studies of pre-eclampsia in ovine placenta' after completing Honours and MSc degrees in embryology.

She has 28 years post doctoral experience - although because of many years working part-time this is approximately equivalent to 15 years post-doctoral experience, and has expertise in morphology/morphometry, vascular grafting and angiogenesis.

In supervising numerous research projects in these areas she has been responsible for the overall design, direction staff and student supervision and manuscript writing and conference presentations for numerous research projects including: the vascular avulsion project (rabbit, human and monkey), the long allograft vein project, the long term vein project, the cold stored artery/vein project, the role of NOS 2 in angiogenesis, mapping angiogenesis in the rat AVL model, the use of PLGA as a scaffold in tissue engineering chambers, triple angiogenic growth factors in angiogenesis and adipogenesis in murine model of tissue engineering.

She is CI on a recently completed and a current NHMRC Research Grant, exploring techniques to improve implanted cell survival in tissue engineering models, and studies of the causes of vascular anomalies.

Contact

Phone :(03) 9288 4030 (Melbourne)
Email :geraldine.mitchell@svhm.org.au
URIs : Staff Directory ProfilePersonal Website

Research Interests

Vascular Biology ; Morphology ; Morphometric techniques ; Morphometrics ; Morphometry ; Vascular Grafting ; Angiogenesis ;

Methods Expertise

No research method is currently recorded.

Research Projects

No research project is currently recorded.

Selected Publications

2011

The influence of nitric oxide synthase 2 on cutaneous wound angiogenesis, in British Journal of Dermatology

Visualisation and stereological assessment of blood and lymphatic vessels, in Histology and Histopathology: cellular and molecular biology

An "off the shelf" vascular allograft supports angiogenic growth in three-dimensional tissue engineering, in Journal of Vascular Surgery

Expansion and Hepatocytic Differentiation of Liver Progenitor Cells In Vivo Using a Vascularized Tissue Engineering Chamber in Mice, in Tissue Engineering. Part C. Methods

2010

Disparate Companions: Tissue Engineering Meets Cancer Research, in Cells Tissues Organs

2008

An endogenously deposited fibrin scaffold determines construct size in the surgically created arteriovenous loop chamber model of tissue engineering, in Journal of Vascular Surgery

2007

Angiogenic Growth Factor Synergism in a Murine Tissue Engineering Model of Angiogenesis and Adipogenesis, in American Journal of Pathology

The arteriovenous loop in a protected space generates a permanent, highly vascular, tissue-engineered construct, in FASEB Journal

2006

The influence of architecture on degradation and tissue ingrowth into three-dimensional poly(lactic-co-glycolic acid) scaffolds in vitro and in vivo, in Biomaterials

Local Shwartzman Reaction in the Rat Induced by Endotoxin and Ischemia: Potential Model for Skin Necrosis in Meningococcemia, in Pediatric Research

Time course analysis of hypoxia, granulation tissue and blood vessel growth, and remodeling in healing rat cutaneous incisional primary intention wounds, in Wound Repair and Regeneration

A method of treatment and compositions useful for same

2005

The use of pimonidazole to characterise hypoxia in the internal environment of an in vivo tissue engineering chamber, in British Journal of Plastic Surgery

2004

Early inducible nitric oxide synthase 2 (NOS 2) activity enhances ischaemic skin flap survival, in Angiogenesis

2002

Angiogenesis in wound healing and surgery, in The new angiotherapy

2001

Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival, in British Journal of Pharmacology