Professor Sandy Middleton - Faculty of Health Sciences (Faculty of Health Sciences)

Fully accredited supervisor - Can supervise as principal supervisor


Evidence-based practice, Health Services research, Stroke, Models of Care. Method: cluster randomised controlled trials, randomised controlled trials, survey methods.


Phone :(02) 8382 3790 (North Sydney)
URIs : Staff Directory Profile

Research Interests

Evidence-Based Practice ; Models of Care ; Health Services Research ; Stroke ;

Methods Expertise

Randomized controlled trials ; Clinical audit ; Survey methods ;

Research Projects

Selected Publications


Management of fever, hyperglycaemia and swallowing dysfunction following acute stroke admission in New South Wales (NSW) Australia, in Interational Journal of Stroke


Thrombolysis ImPlementation in Stroke (TIPS): Evaluating the effectiveness of a strategy to increase the adoption of best evidence practice. Protocol for a cluster randomised controlled trial in acute stroke care, in Implementation Science

Improving quality of life by increasing outings after stroke: Study protocol for the Australian Out-and-About trial, in International Journal of Stroke

Quality in Acute Stroke Care (QASC): Process evaluation of an intervention to improve the management of fever, hyperglycaemia, and swallowing dysfunction following acute stroke, in International Journal of Stroke

Accuracy of case-finding for COPD by practice nurses, in Respirology


A pragmatic cluster randomized controlled trial of early intervention for chronic obstructive pulmonary disease by practice nurse GP teams, in Implementation Science

Determinants of successful clinical networks: the conceptual framework and study protocol, in Implementation Science

Care of patients with a diagnosis of chronic obstructive pulmonary disease: a cluster randomised controlled trial, in Medical Journal of Australia


Predictors of Accuracy of Diagnosis of Chronic Obstructive Pulmonary Disease in General Practice, in Medical Journal of Australia

Implementation of evidence-based treatment protocols to manage fever, hyperglycaemia, and swallowing dysfunction in acute stroke (QASC): a cluster randomised controlled trial, in The Lancet

Other information


2014 - 2016
Arima H, Lavados P, Middleton S, Watkins C, Robinson T, Heritier S, Hackett M, Olavarria V, Heeley, E. Head Position in Stroke Trial (HeadPoST). NHMRC, $1,709,566.

2014 - 2018
Middleton S, Alexandrov A, Watkins C, Cadilhac, D McInnes L.Australian Catholic University - International Stroke Research Collaborative (ACU-ISReC). Australian Catholic University Faculty Research Grant, $ 2,879,428.

2014 - 2016
Spratt N, Ada L, Nilsson M, Middleton S, Bernhardt J, Churilov L, Levi C, Pollack M, Faux S, Perry L, McCluskey A. Altering the Rehabilitation. Altering the Rehabililtation Environment to Improve Stroke Survivor Activity (AREISSA): A Phase II Trial. NSW CVRN Research Development, $254,633.

2013 - 2015
Armstrong E, Godeke E, Bernhardt J, Middleton S, Rai T, Holland A. Very Early Rehabilitation in SpEech: An RCT of aphasia therapy after stroke. NHMRC, $742,000.

2012 - 2016
Middleton S, Levi C, Fitzgerald M, Considine J, Grimshaw J, Da??Este C, Gerraty R, Cheung W, Cadilhac D, McInnes E. Associate Investigators: Quinn C, Cadigan G, Ward J, Longworth M, McElduff P, Dale S, Denisenko S. T3 Trial: Triage, Treatment and Transfer of patients with stroke in emergency departments. NHMRC, $2,258,198.

2012 - 2015
Cadilhac D, Anderson C, Donnan G, Levi C, Thrift A, Middleton S, Lannin N, Faux S, Sundararajan V, Grimley R. STROKE123: A collaborative national effort to monitor, promote and improve the quality of stroke care in hospitals and patient outcomes. NHMRC, $1,200,000.

2012 - 2015
Gardner G, Gardner A, Middleton S, Considine J, Hurst C, Della P, Fitzgerald G, Christofis L, Finckh A, Chu K. A prospective evaluation of the impact of the nurse practitioner role on emergency department service and outcomes. ARC, $507,178.

Cheung W, Campbell L, Middleton S, Pollock C, Fulcher G, Watt H, McElduff P. Diabetes Case Detection through Emergency Department Admissions. NHMRC, $160,016.

2010 - 2012
McCluskey A, Ada L, Middleton S, Goodall S, Grimshaw J, Kelly P. The Out-and-About Trial: Improving quality of life by increasing outdoor journeys after stroke. NHMRC, $576,600.

2010 - 2012
Zwar N, Middleton S, Reddel H, van Schayck CP, Crockett A, Dennis S. Project Grant. A cluster randomised trial of management by a practice nurse - GP team of patients newly diagnosed with COPD. NHMRC, $794,275.

Haines M, Redmond S, ,Castaldi P, Da??Este C, Craig J, Elliott E, Sanson-Fischer R, Scott A. Associate Investigators: Yanos S, Pollock C, Needham K, Middleton S, Paul C, McElduff P. Determinants of Effective Clinical Networks. NHMRC, $338,850.

McCluskey A, Middleton S^. Translating Evidence into Practice: Helping People with Stroke to Get out of the House. NSF, $19,854.

2008 - 2010
Hackett M, Glozier N, Jan S, Lindley R. Associate Investigators: Anderson C, Longworth M. Halliday J, Pollock M, Middleton S, Ada L. Depressive symptoms and return to work after stroke. NHMRC, $471,975.

2008 - 2010
Chan DKY, Levi C, Middleton S, Chen JXC, Cordato D, Pollack M. Project grant. Health Services Research: A Randomised Controlled Trial to evaluate a Model of Comprehensive Stroke Care. NHMRC, $499,450.